Rapid Coronary Vasodilation by Nitroglycerin Tapes.

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Alpha Adrenergic Vasoconstriction and Nitroglycerin Vasodilation of Large Coronary

Dr. Vatner was an Established Investigator, American Heart Association. Dr. Pagani's current address is the University of Milan, Milan, Italy. Received for publication 25 January 1979 and in revised form 6 August 1979. active changes. Alpha adrenergic stimulation is sufficiently powerful to reduce cross-sectional area, despite the opposing elevation of distending pressure.

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Coronary Arteries by Nitroglycerin

Vasodilatory responses of segments of large epicardial left coronary artery (CA), small intramyocardial CAs (0.3-1.0 mm), coronary stenoses and CAs filled by collaterals were determined in 34 patients. Measurements were made before and after nitroglycerin (0.4 mg, sublingual) by means of quantitative magnification coronary angiography using photospot film and a calibrated 6-power viewing device...

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Nitroglycerin-induced coronary vasodilation in cardiac transplant recipients. Evaluation with in vivo intracoronary ultrasound.

BACKGROUND Coronary artery vasomotion is altered after cardiac transplantation. The impact of accelerated transplant coronary atherosclerosis and myocardial rejection on vasomotion is not well understood. Intravascular ultrasound is a new imaging method with the ability to study real-time changes in coronary artery dimensions. METHODS AND RESULTS Epicardial coronary artery response to nitrogl...

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Alpha adrenergic vasoconstriction and nitroglycerin vasodilation of large coronary arteries in the conscious dog.

The effects of methoxamine and nitroglycerin on measurements of large vessel (left circumflex) coronary dimensions were examined in eight conscious dogs using an ultrasonic dimension gauge, and total coronary resistance was calculated from measurements of arterial pressure and coronary blood flow. Methoxamine (50 mug/kg per min), after transiently increasing left circumflex coronary dimensions,...

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Potentiation of nitroglycerin-induced coronary dilatation by N-acetylcysteine.

Previous studies have suggested that (1) nitroglycerin causes vasodilatation by interacting with sulfhydryl groups in vascular smooth muscle, thereby activating guanylate cyclase and increasing the intracellular concentration of cyclic GMP, and (2) N-acetylcysteine, a source of sulfhydryl groups, potentiates the peripheral vasodilatory effect of nitroglycerin. This study was performed to explor...

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ژورنال

عنوان ژورنال: Japanese Heart Journal

سال: 1996

ISSN: 0021-4868,1348-673X

DOI: 10.1536/ihj.37.603